Victoria Smith, Ph.D.

Chief Scientific Officer

Victoria Smith Ph.D. brings over 23 years of experience in biologics drug discovery and development to Amphivena. She began her career in Biotechnology at Genentech, Inc., where she applied her research background in genomics to both target discovery and for the characterization and development of antibody drug conjugates for solid tumors. Dr. Smith then joined Arresto Biosciences at its inception, taking on roles of increasing responsibility with the growth of the company, to become Vice President of Research and Preclinical Development. At Arresto, Dr. Smith led the translation of novel mechanisms for targeting the tumor microenvironment, fibrosis and inflammatory disease to clinical development candidates. Upon the acquisition of Arresto by Gilead Sciences in 2011, Dr. Smith led biologics research and translational studies as the Senior Director of Biologics and Target Biology. 

In the course of her role at Gilead, Dr. Smith built an antibody engineering group, initiated new research projects, provided cross functional Research project support and oversight, supported clinical development for biologics projects from phases 1-3, and continued to deepen her expertise in oncology and immune oncology while also expanding her knowledge in new areas such as virology.

Dr Smith has a B.S. from the University of Western Australia and a Ph.D. from Cambridge University, UK, and she was a Research and Post-Doctoral Fellow at Stanford University in the Departments of Biochemistry and Genetics. She is an author on numerous peer reviewed scientific publications and patents and has received multiple scientific awards.


Curtis L. Ruegg

Curtis Ruegg, Ph.D.

CEO & President

Victoria Smith

Victoria Smith, Ph.D.

Chief Scientific Officer

Patrick Chun

Patrick Chun, M.D.

Vice President

Clinical Development

Amy Penticoff

Amy penticoff, MBA

Vice President

Technical Operations